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Silicified microcrystalline cellulose PROSOLV SMCC



Silicified Microcrystalline Cellulose
 
CAS : 9004-34-6 + 7631-86-9
Manufacturer: JRS PHARMA GmbH & Co. KG

PROSOLV® SMCC is silicified microcristalline cellulose, a patented combination of 98% microcristalline cellulose (MCC) and 2% colloidal silicone dioxide (CSD).

A portfolio of high functionality excipients that imparts superior flow, compaction and dispersion to a formulation. When used in direct compression, PROSOLV® SMCC can replace granulations, while significantly reducing excipient numbers and levels. PROSOLV® SMCC formulations produce distinctive, uniform, cost effective tablets. 


Grade Characteristics Primary Use Other Applications
 PROSOLV
 SMCC® 50
Optimal Compaction
Average Partical Size:
≈60 µ
 
Bulk Density:
≈0,32 g/ml
Tablet binder in direct compression when optimum compaction is needed
•Dry granulation
• Extrusion/Spheronization
•Tablet binders in wet granulation 
 PROSOLV
 SMCC® 90
Balance of Best in Class Compaction  and Flow
Average Partical Size:
≈110 µ
 
Bulk Density:
≈0,32 g/ml
Tablet binder in direct compression for a balance of compaction and flow 
•Capsule Filling
•Post granulation running powder
•Low dose content uniformity
 PROSOLV
 SMCC® HD90
Optimal Flow
Average Partical Size:
≈110 µ
 
Bulk Density:
≈0,42 g/ml
 
Tablet binder in direct compression when optimum flow is needed 
•Increase batch size due to high bulk density
•Improve disintegration
•High dose capsule filling
 PROSOLV
 SMCC® 90 LM
Low humidity < 3 %
Average Partical Size:
≈110 µ
 
Bulk Density:
≈0,37 g/ml
Tablet binder in direct compression of water sensitive  actives
•Capsule Filling
•Post granulation running powder
•Low dose content uniformity