Vitamin E Polyethylene Glycol Succinate, Kolliphor TPGS

Kolliphor TPGS: Solution for insolubility

Kolliphor TPGS – D-alpha tocopheryl polyethylene glycol 1000 succinate (TPGS) – is a water-soluble derivative of vitamin E that can directly enhance the bioavailability of poorly soluble actives. TPGS is commonly used in pharmaceutical and nutraceutical formulations.

Key Features of Kolliphor TPGS
Based on natural-source vitamin E from BASF
Conforms to USP-NF monograph “Vitamin E Polyethylene Glycol Succinate”
Produced according to IPEC-PQG GMP guidelines
No chlorinated solvents used
Detailed technical and regulatory information available

Enhanced delivery of life-saving drugs
 Kolliphor TPGS directly increases the bioavailability and delivery of poorly soluble drugs.
TPGS can be used in oral, topical and parenteral dosage forms.
It is also used in dietary supplements, cosmetic applications and food.

Key benefits for customers
Cognis is a leading supplier of natural-source vitamin E and pharma-grade excipients, and has considerable expertise in solubilizers.
 Using its own vitamin E feedstocks, BASF guarantees consistent quality and a competitive, reliable supply of TPGS.
 In accordance with stringent industry requirements, BASF maintains the highest manufacturing standards, with full supporting documentation.
 TPGS from BASF offer high solubilisation effectiveness.
 BASF offers a global sales network plus technical and regulatory support.

Applications:
-Drug solubilizer
-Absorption enhancer
-Emulsifier
-Vehicle for lipid-based drug delivery
-Source of natural vitamin E
-Antioxidant

Files for download:

Technical Information