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Microcrystalline Cellulose Vivapur, Heweten, Emcocel



Microcrystalline Cellulose, Ph.Eur., NF, JP
RO-CEP-2009-321  
CAS : 9004-34-6
Manufacturer JRS PHARMA GmbH & Co. KG

Microcrystalline cellulose is purified, partially depolymerize cellulose is a white or almost white, odorless, tasteless crystalline powder, consisting of porous particles. Grades of microcrystalline cellulose are of  different particle size and moisture content, have different properties and fields of application.

  Average Particle Size by laser diffraction (µm)


Bulk Density (g/cm3)

Main Application
Air Stream Dried
Quality
Spray
Dried Quality
VIVAPUR® EMCOCEL®
VIVAPUR® 105   25 0.20 - 0.26   Very fine grade, which gives a pleasant mouth feeling, masks bitter tastes and supports flavors.

VIVAPUR® 101, HEWETEN®101

EMCOCEL®50M 

65  0.26 - 0.31 0.25 - 0.37 Fine standard MCC grade, especially suited for wet granulation, roller compaction and spheronization. Very high compactibility.
VIVAPUR® 101 Premium   65  0.26 - 0.31   Same grade as 101 but very low amount of visable specks and high degree of brightness.
 VIVAPUR® 103 EMCOCEL® LM50 65 0.26 - 0.34 0.25 - 0.37 Same quality as grade 101/50M, but very low moisture content (< 1.5% resp. 3%) for processing water-sensitive actives.
VIVAPUR®  301   65  0.35 - 0.46   Same quality as grade 101, but increased bulk density and improved flow properties.
 VIVAPUR® 102, HEWETEN®102 EMCOCEL® 90M 100 0.28 - 0.33 0.25 - 0.37 Medium size standard MCC grade, suited for the majority of directly compressible actives. Combines good flow and high compactibility.

 VIVAPUR® 102 Premium

  100 0.28 - 0.33   Same grade as 102 but very low amount of visable specks and high degree of brightness.
VIVAPUR® 112  EMCOCEL® XLM90 100  0.30 - 0.36 0.25 - 0.37 Same quality to grades 102/90M, but very low moisture content (< 1.5%) for pro-cessing water-sensitive actives. 
 VIVAPUR® 302 EMCOCEL® HD90 100 0.35 - 0.50 0.38 - 0.50 Same quality to grade 102/90M, but increased bulk density and improved flow properties. Especially suited for high speed tableting and processing high density actives.
The Innovative MCC- Grade for Direct Compression
VIVAPUR® 12   180  0.30 - 0.36   Coarse grade MCC, combines good compactibility and high binding capacity with outstanding flow. Provides good content uniformity at low weight variation - even when used with low concentrations of fine actives.
VIVAPUR® 14   180 0.34 - 0.42   Same quality to grade 12, but very low moisture content (<1,5%) for processing water-sensitive actives.
  EMCOCEL® LP200 190   0.25 - 0.37 Coarse grade MCC, combines good com-pactibility and high binding capacity with outstanding flow. Provides good content uniformity at low weight variation - even when used with low concentrations of fine actives.
 VIVAPUR® 200   250 0.31 - 0.37  

Large size MCC grade with excellent flow properties for a variety of direct
compression formulations.

 VIVAPUR® XLM200   250 0.33 - 0.40   Same quality to grades 200/LP200, but very low moisture content (<1,5%) for processing water-sensitive actives.